Recurrent outbreaks of herpes simplex virus 2 (HSV2) or “genital herpes” can be treated effectively with a one-day therapy with valacyclovir (Valtrex), according to results of a pilot study published in the journal Sexually Transmitted Diseases.

To Dr. Stephen K. Tyring, Center for Health Sciences at the University of Texas in Houston, brought together 115 patients with recurrent HSV2 infection.

Patients received therapy one-day valacyclovir 4,000 milligrams (mg) in two doses of 2,000 mg, at the earliest signs of recurrence.

Participants performed monitoring the duration of their symptoms in diaries and collected genital swabs for viral cultures that were made 14 days after initiation of therapy.

Tyring’s team reports that 90 patients (78 percent) had a recurrence or signs of onset of symptoms and four patients (5 percent) developed a second recurrence after 14 days of treatment with valacyclovir.

The median duration of genital pain and inflammation was five and three days, respectively.

“Treatment of a day appears to be as effective as three to five days” said Tyring Reuters Health in an interview.

The team concluded that the regimen of valacyclovir day “be a convenient treatment for recurrent genital herpes.

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Image: Christine McIntoshLas disease transmitted by tick bites is relatively common in our geography, especially in rural areas or among dog owners. Every year they come to diagnose cases of spotted fever or Lyme disease. Now a group of Spanish researchers has patented a method for the rapid diagnosis of bacterial diseases transmitted by the bites of small arthropods common.

Disease Detection

Researchers at the National Microbiology Center (CNM) have received the award for best evident in the V Awards Madrid, by creating a method for detecting bacterial species through DNA analysis, which allows a quick diagnosis diseases transmitted by biting lice, ticks and fleas. Pedro Anda, Laboratory of Spirochetes, CNM Special Pathogens and lead investigator, said that the bacteria transmitted by the bites of small arthropods “produce very significant health problems and their combined impact is relatively high.”

The detection kit allows the identification of several diseases caused by more than 50 bacterial species grouped in seven specific genres ( “Anaplasma,” “Borrelia” “Bartonella” “Coxiella”, “Arliqueia” “Francisella” and “Rickettsiav) . These bacteria are associated with diseases such as spotted fever or Lyme disease. This method facilitates the detection and classification, factors of great importance to find preventive solutions.

Also, the kit can establish protocols that allow rapid forestall the emergence of cases because, within hours of infection, conclusive results are available that allow early treatment of disease and thus avoid complications and subsequent sequels. In addition, the new system identifies pathogens based on geographic region, so that you can set action plans and prevention to avoid the appearance of new affected.

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They have done by transplanting the patient’s own epidermal cells of a pigmented area on certain areas which appear depigmented. “The novelty of this method is that we grow epidermal cells in monolayer on a substrate of amniotic membrane,” explains Pedro Redondo, Pamplona center of that dermatologist and director of the work whose results were published in the official magazine of the British Association of Dermatologists. As noted, his team has treated ten patients with stable vitiligo by transplantation of these cells, and all have achieved high success rates, “witha repigmentation of 75 to 100 percent of the affected area.

As stated by Felipe Prosper, area director of the Clinical Cell Therapy, the treatment of vitiligo by this new technique begins with the cultivation of epidermal cells and keratinocyte-demelanocitos mixture, to then proceed to make selective crops. “To date there were no jobs in monolayer cultures of melanocytes because they had not found adequate support to achieve them,” says Prosper. In addition, Redondo stresses that “the best indication is the treatment of targeted areas, who have not responded to conventional medical treatments.

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A wide variety of substances can cause a skin condition called contact dermatitis, which is often controlled with a proper diagnosis and treatment, experts say.

Contact dermatitis is a chronic or acute inflammation of the skin resulting from contact with a chemical, biological, or physical. The most common culprits include cosmetics, perfumes, certain foods, nickel and other metals, cleaning solutions and detergents, industrial chemicals and rubber latex.

The majority (between 20 and 35 per cent) of cases of dermatitis affecting the hands, including over 75 percent of cases of contact dermatitis related to the workplace, according to experts at the annual meeting of the American College of Allergy, Asthma & Immunology (ACAAI) in Seattle.

“Allergic contact dermatitis of the hands is very common in certain trades. As such health professionals, hairdressers and cosmetologists, carpenters, machine operators or those working with chemicals,” said Dr. James. S. Taylor, director of the Section of industrial dermatology at the Cleveland Clinic in Ohio, in a press release from the ACAAI.

Patch tests are important in the diagnosis of hand dermatitis, as allergic contact dermatitis may appear alone or with irritant dermatitis, atypical or otherwise, Taylor said. Treatment depends on the cause of dermatitis.

“To relieve the symptoms of allergic contact dermatitis, it is necessary to omit or substitute or use the allergen usually topical or systemic corticosteroids occasionally,” said Taylor.

The second most common site for dermatitis is the face and eyelids, often due to a reaction to a cosmetic, soap or other personal care product.

“The patient has to change to a new brand of makeup or a different cleaner before you see the skin rash. Normally, we treat this condition with a topical corticosteroid and we tell the patient to stop using the product,” stated Dr. Vincent A. DeLeo, chief of dermatology at Beth Israel Medical Center and St. Luke’s-Roosevelt in New York City, in the press release of the ACAAI.

Usually the patch test is not required in cases of dermatitis of the face and eyelids, but may be required if the patient does not improve after switching products skin care and topical treatment, said DeLeo.

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